Hand-arm vibration exposure is a recognized occupational hazard that can cause discomfort and long-term disorders. While anti-vibration gloves are commonly used to reduce these effects, their effectiveness is often limited by the stiffness of the materials and structural constraints. This study focuses on the development and evaluation of polydimethylsiloxane (PDMS)- based anti-vibration layers with varying internal structures for use in anti-vibration gloves. We prepared three types of PDMS layers: solid PDMS without pores (SPDMS), porous PDMS foam created through a sugar-leaching process (FPDMS), and a hybrid PDMS structure that combines solid and porous layers (HPDMS), all shaped like palms. These PDMS layers were integrated into glove specimens, and their vibration transmissibility was assessed using a measurement system compliant with ISO 10819:2013. Vibration transmissibility was recorded across one-third octave bands from 25 to 1,250 Hz, and frequency-weighted transmissibility values were calculated for both the M- and H-spectra. The results indicate that PDMSbased anti-vibration layers with controlled porosity can be effectively fabricated and incorporated into glove structures, and that variations in internal porosity significantly impact the measured vibration transmissibility characteristics.