This study quantitatively investigates the deviation between the ideal and effective amplification ratios of a bridge-type displacement amplification mechanism used in ultra-precision positioning systems. It proposes region-specific optimal design strategies to mitigate this deviation. A Leave-One-Out sensitivity analysis reveals that the dominant factor influencing amplification ratio deviation shifts at an ideal amplification ratio of approximately 10. In the high-amplification region (R > 10), displacement loss due to bending of the input link is identified as the primary cause of deviation. Reinforcing the input link's thickness and incorporating a pocket structure reduces the deviation to within 12.4% while minimizing resonance frequency degradation. Conversely, in the low-amplification region (R < 7), the main issue is dynamic performance deterioration caused by oversized intermediate links. Implementing a hexagonal mass-reduction design enhances the first resonance frequency by up to 28% without compromising the amplification ratio. These findings establish differentiated design guidelines based on the target amplification ratio, enabling simultaneous improvements in precision and dynamic performance for bridge-type displacement amplification mechanisms in positioning systems.